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(More customer reviews)Recently the book "Clinical epidemiology. Principles, methods and applications for clinical research" was published. The authors and contributors are know for their high quality clinical epidemiological research which has find its way to many high impact medical journals. They not only have contributed to the knowledge base of medicine but also to the knowledge base of the methodology of clinical epidemiology. With this in mind and with my background as a clinical epidemiologist and clinician, I have read the book.
The book has a sound and helpful structure. They divided the book in principles of clinical research and the tools for clinical research. In the overview that precedes these two parts, they present an overview in which they give their conceptual framework of clinical epidemiology. This framework is used throughout the book and helps to understand many of the principles. This framework also has strong roots in daily clinical work and principles of clinical practice. This starting point, the many clinical examples from a diversity of medical subspecialties, the clear style and the fundamental relevance of clinical epidemiology for clinical practice makes it attractive for clinicians from many fields. A further division in etiologic, diagnostic, prognostic and intervention research makes it even more accessible for clinicians.
Their description of the tools for clinical research again shows their understanding of the field. Not only do they describe, explain and illustrate with examples but also discuss aspects that have not been settled. They take position based on arguments and their conceptual framework but do not become dogmatic. The part "tools for clinical research" is complete and up-to-date and includes fairly new designs like the case-crossover design and case-control studies with no controls as is used in gene-environment interaction studies. The book is completed with a chapter on meta-analysis and on clinical epidemiologic data analysis. They give a glimpse of the future of data analysis by quoting: "The advantages of the Bayesian approach are so important and so natural to medical reasoning that in the near future the frequentist's way of analysis in clinical epidemiology is likely to largely be replaced by Bayesian techniques.". Again showing that they have written a book that is balanced and strongly rooted both in clinical practice and clinical epidemiology and again showing their contribution to the development of clinical epidemiology.
This book will undoubtedly find its way to many professionals involved in the design and conduct of clinical research as well as to undergraduates and graduates in medicine and all those clinicians who need to critically appraise the available evidence in order to provide high quality patient care. They will notice that "all scientific medical articles are equal, but some are more equal than others" (free after George Orwell).
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In the current era of evidence-based medicine, clinical epidemiology is increasingly recognized as an essential tool in the critical appraisal of available evidence and the design of new studies. Clinical Epidemiology: Principles, Methods, and Applications for Clinical Research is a comprehensive resource that introduces the reader to the basics of clinical epidemiology and explores the principles and methods that can be used to obtain quantitative evidence on the effects of interventions and on the diagnosis, etiology, and prognosis of disease. The everyday challenges of clinical research and the quantitative knowledge required to practice medicine are also examined, making this book a valuable reference for both graduate and undergraduate students in medicine and related disciplines, as well as for professionals involved in the design and conduct of clinical research.
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